Elektronik ve Haberleşme Mühendisliği Bölümü Yayın Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12416/260
Browse
Browsing Elektronik ve Haberleşme Mühendisliği Bölümü Yayın Koleksiyonu by WoS Q "Q1"
Now showing 1 - 5 of 5
- Results Per Page
- Sort Options
Article Citation - WoS: 48Citation - Scopus: 50High-Throughput Screening of Large Volumes of Whole Blood Using Structured Illumination and Fluorescent On-Chip Imaging(Royal Soc Chemistry, 2012) Arpali, Serap Altay; Arpali, Caglar; Coskun, Ahmet F.; Chiang, Hsin-Hao; Ozcan, AydoganUndiluted blood samples are difficult to image in large volumes since blood constitutes a highly absorbing and scattering medium. As a result of this limitation, optical imaging of rare cells (e.g., circulating tumour cells) within unprocessed whole blood remains a challenge, demanding the use of special microfluidic technologies. Here we demonstrate a new fluorescent on-chip imaging modality that can rapidly screen large volumes of absorbing and scattering media, such as undiluted whole blood samples, for detection of fluorescent micro-objects at low concentrations (for example <= 50-100 particles/mL). In this high-throughput imaging modality, a large area microfluidic device (e.g., 7-18 cm(2)), which contains for example similar to 0.3-0.7 mL of undiluted whole blood sample, is directly positioned onto a wide-field opto-electronic sensor-array such that the fluorescent emission within the microchannel can be detected without the use of any imaging lenses. This microfluidic device is then illuminated and laterally scanned with an array of Gaussian excitation spots, which is generated through a spatial light modulator. For each scanning position of this excitation array, a lensfree fluorescent image of the blood sample is captured using the opto-electronic sensor-array, resulting in a sequence of images (e.g., 144 lensfree frames captured in similar to 36 s) for the same sample chip. Digitally merging these lensfree fluorescent images based on a maximum intensity projection (MIP) algorithm enabled us to significantly boost the signal-to-noise ratio (SNR) and contrast of the fluorescent micro-objects within whole blood, which normally remain undetected (i.e., hidden) using conventional uniform excitation schemes, involving plane wave illumination. This high-throughput on-chip imaging platform based on structured excitation could be useful for rare cell research by enabling rapid screening of large volume microfluidic devices that process whole blood and other optically dense media.Article Hydrogen hosting of nanoscale boron cluster(Editura Academiei Romane, 2008) Böyükata, Mustafa; Özdoğan, C.; Güvenç, Ziya B.In this paper the Density Functional Results of hydrogen bonded boron micro clusters with B3LYP/6-311++G(d,p) level of computations will be presented. Energetics and structural stability with their possible stable geometries of various selected micro complexes of B(m)H(n) (for m and n <= 11 )boron hydrides have been analysed, and their binding energies with HOMO-LUMO energy gaps have been determined. Mainly, erects of the number of hydrogen atoms on the structures of the boranes are assessed. Moreover, for the cage configurations their distortions have been investigated for the neutral, anionic and cationic cases. It has been observed that there have been two opposing factors for the cage configurations. One of which is the "peeling" of the cage structures by the hydrogen atoms, and the other one is reforming a smaller cage form simultaneously with there remaining boron atoms inside. This is observed mostly for the odd values of m. From our studies it has been also observed that with the bare boronclusters alone, it is difficult to increase the capacity of the hydrogen storage. Therefore, further studies are necessary with the boron complexesArticle Citation - WoS: 22Citation - Scopus: 20The Method of Transition Boundary for the Solution of Diffraction Problems(Springer, 2019) Umul, Yusuf ZiyaA new method, which enables one to solve some diffraction problems, is put forth. The technique is based on a relation between the diffracted and scattered geometric optics waves at the transition boundaries. The concept of initial waves is also used instead of the incident field. The general algorithm of the method is outlined and applied to the diffraction problems of waves by perfect electric conductor half-screen, resistive half-plane and impedance sheet junction.Article Citation - WoS: 33Citation - Scopus: 36Mtpo Based Potential Function of the Boundary Diffraction Wave Theory(Elsevier Sci Ltd, 2008) Umul, Yusuf Z.A novel potential function is introduced by using the modified theory of physical optics integrals for a perfectly conducting half-plane. The function is valid for arbitrary aspects of observation. The line integration of these functions gives the total scattered fields. The method is applied to the problem of diffraction of plane waves by an opaque half-plane for oblique incidence. (c) 2008 Elsevier Ltd. All rights reserved.Article Citation - WoS: 1Citation - Scopus: 1Speckle Contrast for Flat-Topped Field Profiles(Elsevier Sci Ltd, 2013) Baykal, YahyaSpeckle contrast is evaluated for flat-topped field profiles where the characterization and evaluation of speckle contrast are based on mathematical formulation and theoretical parameter variation. The speckle field which is represented by the random phase shift and the random phase tilt is multiplied by the flat-topped shaped field. The increase in the source size of the flat-topped field first causes the speckle contrast to increase, then reaches saturation. Increase in the variance of the phase shift of a flat-topped field causes an appreciable increase in the speckle contrast. Depending on the diffraction characteristics of the finite sized flat-topped field distribution, upon changing the variance of the phase shift, the speckle contrast exhibits different behavior at short and long propagation distances. However, especially for small variances of phase tilts, the speckle contrast seems to monotonically increase as the propagation distance becomes larger. The effect of the order of flatness on the speckle contrast is small at short propagation distances which can be appreciable at long propagation distances. (C) 2012 Elsevier Ltd. All rights reserved.
