Makine Mühendisliği Bölümü Yayın Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12416/263

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Author: search.filters.author.Yıldırım, EnderHas files: No

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Now showing 1 - 9 of 9
  • Conference Object
    Citation - Scopus: 1
    A Droplet Based Multi-Drug Screening System Controlled With Electrostatic Microvalves
    (Chemical and Biological Microsystems Society, 2012) Yildirim, E.; Yıldırım, Ender; Özgür, E.; Külah, H.; Makine Mühendisliği
    This paper presents a droplet-based drug effect analysis system utilizing electrostatically-actuated normallyclosed microvalves to screen the effect of multiple drugs on a single type of cell. Proposed system minimizes the need for off-chip equipment by utilizing parylene based electrostatic microvalves. Prototypes of the system were fabricated and tested using colored DI water and 3 μm diameter micro beads, emulating drugs and cells respectively. During the tests, micro beads could be successfully entrapped in 137 pl droplets. Tests carried out with yeast cells also yielded successful encapsulation of the cells. It was shown that, switching between the drugs could be achieved by applying 200 V dc to operate the microvalves.
  • Conference Object
    Droplet Based Cell Screening System Integrated With Cmos Image Sensor and Android-Based Application
    (Chemical and Biological Microsystems Society, 2020) Yıldırım, Ender; Özkan, M.D.; Aslan, M.K.; Atik, A.C.; Özgür, E.; Yıldırım, E.; Külah, H.; Makine Mühendisliği
    This paper presents a droplet based single cell screening concept, where the cells encapsulated in microdroplets are monitored by integrating a commercial CMOS image sensor to the microfluidic chip. The images acquired through the image sensor are streamed and processed via an Android-based application on smartphone. This integrated system offers microscope-free screening of cells within the droplets based on their shapes. © 17CBMS-0001.
  • Conference Object
    Fluorescent On-Chip Imager by Using a Tunable Absorption Filter
    (Ieee, 2017) Arpali, Caglar; Yıldırım, Ender; Yildirim, Ender; Arpali, Çağlar; Arpali, Serap Altay; Arpali, Serap; Makine Mühendisliği; Mekatronik Mühendisliği; Elektronik ve Haberleşme Mühendisliği
  • Conference Object
    Citation - WoS: 12
    Citation - Scopus: 13
    A Reconfigurable Microfluidic Transmitarray Unit Cell
    (Ieee, 2013) Erdil, Emre; Yıldırım, Ender; Topalli, Kagan; Zorlu, Ozge; Toral, Taylan; Yildirim, Ender; Kulah, Haluk; Civi, Ozlem Aydin; Makine Mühendisliği
    This paper presents a novel microfluidics based approach to develop a reconfigurable circularly polarized transmitarray unit cell. The unit cell comprises double layer nested split ring slots formed as microfluidic channels that can be filled by fluids. Split regions in the slots are realized by injecting liquid metal into the channels. Beam steering is obtained by implementing rotational phase shifting via manipulating the liquid metal in the slots. X-band unit cell prototypes are fabricated on glass substrate carrying a patterned metal film, and the slot channels are formed by Polydimethylsiloxane (PDMS) using soft lithography techniques.
  • Conference Object
    Phaseguide Assisted Liquid Lamination for Magnetic Bead-Based Assays
    (Chemical and Biological Microsystems Society, 2013) Phurimsak, C.; Yıldırım, Ender; Yildirim, E.; Trietsch, S.J.; Hankemeier, T.; Tarn, M.D.; Pamme, N.; Vulto, P.; Makine Mühendisliği
    We demonstrate a simple, pump-free platform for performing rapid magnetic bead-based processes via their transfer through sequentially laminated liquid streams, made possible by the use of phaseguide technology. We have applied this strategy to two on-chip assays: (i) a streptavidin-biotin binding assay, and (ii) a sandwich immunoassay for the detection of C-reactive protein (CRP). Here, functionalized magnetic beads were pulled through alternating lanes of reagents and buffer solution, allowing multiple binding and washing processes to be reduced into a single step, significantly shortening procedural times compared to conventional multi-step bead-based assays.
  • Conference Object
    Microchip Based Determination of Bacteria by In Chip Sandwich Immunoassay International Multidisciplinary Symposium on Drug Research and Development
    (2015) Kasap, Esin; Çoğun, Ferah; Yıldırım, Ender; Boyacı, İsmail Hakkı; Çetin, Demet; Suludere, Zekiye; Tamer, Uğur; Ertaş, Nusret
  • Conference Object
    Simultaneous Detection of Two Different Bacteria Using QDs and MNPs
    (2016) Doğan, Üzeyir; Kasap, Esin Nagihan; Çoğun, Ferah; Yıldırım, Ender; Çetin, Demet; Suludere, Zekiye; Boyacı, İsmail Hakkı; Ertaş, Nusret; Tamer, Uğur
  • Conference Object
    Chip-Based Immunomagnetic Separation of Human Chorionic Gonadotropin
    (2016) Ahi, Elçin Ezgi; Gümüştaş, Aysen; Çiftçi, Hakan; Çağlayan, M. Gökhan; Somay Selbes, Yeşim; Çoğun, Ferah; Yıldırım, Ender; Tamer, Uğur
  • Article
    MEMS Malzeme karakterizasyonu için bütünleşik bir elektrostatik mikro bükülme test yapısı tasarımı ve gerçekleştirilmesi
    (Çankaya Üniversitesi, 2012) Yıldırım, Ender; Akın, Tayfun; Arıkan, M. A. Sahir
    Mikro elektromekanik sistemlerde kullanılan malzemelerin mekanik özelliklerinin, üretim yöntemleri nedeniyle, mikro boyuttaki test yapılarıyla tespit edilmesi gerekmektedir. Bu çalışmada, eyleyici, test numunesi ve ölçüm skalası tek bir yonga üzerinde bütünleşik olarak üretilmiş bir mikro bükülme test yapısı sunulmaktadır. Tüm bileşenlerin bütünleşik olarak üretilmiş olması, benzer sistemlerde gözlenen hizalama problemini ortadan kaldırmaktadır. Yapı, iki uçtan ankastre mesnetli bir test kirişinin orta noktasından tarak tipi bir elektrostatik eyleyici ile çekilmesi esasına dayanmaktadır. Bükülme miktarı, ölçüm skalası üzerinden, görüntü işleme yöntemleri kullanılarak tespit edilmektedir. Tasarlanan yapılar yalıtkan-üzeri-silisyum pullar kullanılarak üretilmiştir. Testler sonucunda, literatürde belirtilen sonuçlarla uyumlu olarak, silisyum elastik modülü 136 GPa olarak belirlenmiştir