Makine Mühendisliği Bölümü Yayın Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12416/263

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  • Conference Object
    Citation - Scopus: 1
    A Droplet Based Multi-Drug Screening System Controlled With Electrostatic Microvalves
    (Chemical and Biological Microsystems Society, 2012) Yildirim, E.; Yıldırım, Ender; Özgür, E.; Külah, H.; Makine Mühendisliği
    This paper presents a droplet-based drug effect analysis system utilizing electrostatically-actuated normallyclosed microvalves to screen the effect of multiple drugs on a single type of cell. Proposed system minimizes the need for off-chip equipment by utilizing parylene based electrostatic microvalves. Prototypes of the system were fabricated and tested using colored DI water and 3 μm diameter micro beads, emulating drugs and cells respectively. During the tests, micro beads could be successfully entrapped in 137 pl droplets. Tests carried out with yeast cells also yielded successful encapsulation of the cells. It was shown that, switching between the drugs could be achieved by applying 200 V dc to operate the microvalves.
  • Conference Object
    Droplet Based Cell Screening System Integrated With Cmos Image Sensor and Android-Based Application
    (Chemical and Biological Microsystems Society, 2020) Yıldırım, Ender; Özkan, M.D.; Aslan, M.K.; Atik, A.C.; Özgür, E.; Yıldırım, E.; Külah, H.; Makine Mühendisliği
    This paper presents a droplet based single cell screening concept, where the cells encapsulated in microdroplets are monitored by integrating a commercial CMOS image sensor to the microfluidic chip. The images acquired through the image sensor are streamed and processed via an Android-based application on smartphone. This integrated system offers microscope-free screening of cells within the droplets based on their shapes. © 17CBMS-0001.
  • Conference Object
    Citation - Scopus: 4
    Small-Scale Mechanical Properties of Additively Manufactured Ti-6al
    (The University of Texas at Austin, 2020) Totuk, Onat Halis; Haghshenas, M.; Totuk, O.; Masoomi, M.; Thompson, S.M.; Shamsaei, N.; Mekatronik Mühendisliği
    This article aims at studying microstructure and nano/micro-scale mechanical responses of Ti-6Al4V fabricated using a Laser-based Powder Bed Fusion (L-PBF) method. To this end, an instrumented depth-sensing nanoindentation system has been used to assess hardness, Young's modulus, strain rate sensitivity and rate dependent plastic deformation of the alloy at different build Orientations (in the Z-plane and X-plane) at ambient temperature. Indentation tests were conducted at constant proportional loading rate of 15 mN/s in a depth-controlled (hind=2000 nm) testing regime. The Microstructure characterizations were performed using optical and scanning electron microscopy to assess the correlations to the mechanical properties achieved by the nanoindentation testing to better establish structure-property relationships for L-PBF Ti-6Al-4V. It is expected that the fine microstructure, developed by fast solidification during the L-PBF process, to directly contribute to the nanoindentation measurements at different strain rates. Copyright © SFF 2017.All rights reserved.
  • Conference Object
    Fluorescent On-Chip Imager by Using a Tunable Absorption Filter
    (Ieee, 2017) Arpali, Caglar; Yıldırım, Ender; Yildirim, Ender; Arpali, Çağlar; Arpali, Serap Altay; Arpali, Serap; Makine Mühendisliği; Mekatronik Mühendisliği; Elektronik ve Haberleşme Mühendisliği
  • Conference Object
    Citation - WoS: 12
    Citation - Scopus: 13
    A Reconfigurable Microfluidic Transmitarray Unit Cell
    (Ieee, 2013) Erdil, Emre; Yıldırım, Ender; Topalli, Kagan; Zorlu, Ozge; Toral, Taylan; Yildirim, Ender; Kulah, Haluk; Civi, Ozlem Aydin; Makine Mühendisliği
    This paper presents a novel microfluidics based approach to develop a reconfigurable circularly polarized transmitarray unit cell. The unit cell comprises double layer nested split ring slots formed as microfluidic channels that can be filled by fluids. Split regions in the slots are realized by injecting liquid metal into the channels. Beam steering is obtained by implementing rotational phase shifting via manipulating the liquid metal in the slots. X-band unit cell prototypes are fabricated on glass substrate carrying a patterned metal film, and the slot channels are formed by Polydimethylsiloxane (PDMS) using soft lithography techniques.
  • Conference Object
    Neck Protection in Autonomous Car Crashes
    (Kauno Technologijos Universitetas, 2020) Yavuz, Samet; Yavuz, S.; Himmetoglu, S.; Makine Mühendisliği
    Autonomous cars which are expected to be on the market in the upcoming years, present new challenges to restraint system design since unconventional seating plans can put the occupants at more risk. For instance, an occupant sitting on a rear facing seat can experience higher risk of whiplash in a frontal impact considering the fact that statistically frontal impacts do happen at higher severities than rear impacts as seen in the crash test conditions of US NCAP. In this study, an improvement to car seat design is presented in which the seatback is automatically rotated into a more upright position prior to impact in order to increase the energy absorbing potential of the seatback. The study involves computer simulation of a seat-occupant system to demonstrate the benefits of the proposed system. © 2020 Kaunas University of Technology. All rights reserved.
  • Conference Object
    Phaseguide Assisted Liquid Lamination for Magnetic Bead-Based Assays
    (Chemical and Biological Microsystems Society, 2013) Phurimsak, C.; Yıldırım, Ender; Yildirim, E.; Trietsch, S.J.; Hankemeier, T.; Tarn, M.D.; Pamme, N.; Vulto, P.; Makine Mühendisliği
    We demonstrate a simple, pump-free platform for performing rapid magnetic bead-based processes via their transfer through sequentially laminated liquid streams, made possible by the use of phaseguide technology. We have applied this strategy to two on-chip assays: (i) a streptavidin-biotin binding assay, and (ii) a sandwich immunoassay for the detection of C-reactive protein (CRP). Here, functionalized magnetic beads were pulled through alternating lanes of reagents and buffer solution, allowing multiple binding and washing processes to be reduced into a single step, significantly shortening procedural times compared to conventional multi-step bead-based assays.
  • Conference Object
    Yüksek Sıcaklık Pem Yakıt Hücresi Mikro-Kojenerasyon Sistemi Tasarımı
    (2016) Devrim, Yılser; Üregen, Nurhan; Özgirgin Yapıcı, Ekin
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  • Conference Object
    Microchip Based Determination of Bacteria by In Chip Sandwich Immunoassay International Multidisciplinary Symposium on Drug Research and Development
    (2015) Kasap, Esin; Çoğun, Ferah; Yıldırım, Ender; Boyacı, İsmail Hakkı; Çetin, Demet; Suludere, Zekiye; Tamer, Uğur; Ertaş, Nusret