Matematik Bölümü Yayın Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12416/413
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Article Spectrophotometry simultaneous determination of levamisole and triclabendazole in tablets by principal component regression and partial least squares chemometric methods(Chiminform DATA S A, 2008) Pektas, Gözde; Dinç, Erdal; Baleanu, DumitruPrincipal component regression (PCR) and partial least squares (PLS) chemometric methods were applied to the simultaneous quantitative analysis of levamisole (LVM) and triclabendazole (TCB) in tablets without using a preliminary separation, even in presence of the overlapping spectra of the above compounds. For both PCR and PLS, a concentration set containing 25 different mixtures of LVM and TCB in the linear concentration range was symmetrically prepared and then the absorbance values of the concentration set were measured at the wavelength set with Δλ=0.1 nm in the spectral region of 225-322.3 nm. PCR and PLS calibrations were obtained by applying the PCR and PLS algorithms to the concentration set data (y-block) and their corresponding absorbance data (x-block). The validity of PCR and PLS chemometric methods was performed by using the independent synthetic mixtures and the standard addition technique. Then, these analytical methods were applied to the commercial tablets and a good agreement was obtained between experimental results provided by the application of the PCR and PLS to the synthetic and real samples.Article Symmetrically substituted zinc phthalocyanine derivatives bearing N-heterocycle moieties: Synthesis and structural analysis investigations(Chiminform DATA S A, 2014) Youssef, Tamer E.; Al-Turaif, Hamad; Baleanu, DumitruZinc(II)phthalocyanines bearing N-heterocycle moieties units were synthesized and characterized. Their Fourier transform infrared spectroscopic data were compared in order to characterize the investigated spectra. Fuzzy C-Means clustering technique was applied to extract some new information about these data. Hay synthesis of a novel series of symmetrically substituted zinc phthalocyanine derivatives, [(heteroxy)8ZnPcs] 4(α-e) bearing N-heterocycle moieties, i.e. Imidazol, Thiazol, Piperazine and Tetrazol rings, was reported. Their novel heterocycle-oxyphthalonitrile precursors 3(α-e) were synthesized by the aromatic nucleophilic substitution reaction of 4,5-dichlorophthalonitrile with hetero-substituted phenols 2(α-e). The structure of the compounds was revealed by the spectroscopic analysis tools, in addition some hidden similarities of the raw spectra were revealed within the Fuzzy C-Means clustering technique.