WoS İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12416/8653
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Article A Meta-Heuristic Stochastic Algorithm for the Numerical Treatment of Cancer Model through the Chemotherapy and Stem Cells(Elsevier, 2026) Baleanu, Dumitru; Defterli, Ozlem; Sabir, Zulqurnain; Abdelkawy, M. A.Objective: The aim of current research is to present the numerical performances of the cancer treatment model based on chemotherapy and stem cells using one of the heuristic computing neural network procedures. The cancer treatment model through chemotherapy and stem cells is categorized into stem cells, affected cells, tumor cells, and chemotherapy-based concentration drug. Method: A process of artificial neural network is applied using the hybrid optimization of global and local search schemes, which are taken as genetic algorithm (GA) and an active set (AS). An error-based fitness function is designed by using the differential model and then optimized by the hybridization of both global and local search schemes. GA is applied to exploit the global result and give a primary guess to the AS that further improves the results locally. AS is rooted in the GA, where GA produces new populaces and AS optimizes the fitness function for every individual. The hybridization of these two schemes is used iteratively for purifying the results. Ten numbers of neurons and log-sigmoid activation functions has been used to solve the cancer treatment model based on chemotherapy and stem cells. Results: For the correctness of the stochastic solver, the obtained numerical results have been compared with any traditional scheme. Moreover, the reliability and capability of the scheme are performed through the absolute error around 10-05 to 10-07 along with different statistical approaches for solving the mathematical model. Novelty: The proposed artificial neural network structure along with the hybrid optimization of global and local search schemes has never been implemented before to solve the cancer treatment model based on chemotherapy and stem cells.Article Citation - WoS: 8Citation - Scopus: 9Numerical Computational Heuristic Through Morlet Wavelet Neural Network for Solving the Dynamics of Nonlinear Sitr Covid-19(Tech Science Press, 2022) Alnahdi, Abeer S.; Jeelani, Mdi Begum; Abdelkawy, Mohamed A.; Raja, Muhammad Asif Zahoor; Baleanu, Dumitru; Hussain, Muhammad Mubashar; Sabir, ZulqurnainThe present investigations are associated with designing Morlet wavelet neural network (MWNN) for solving a class of susceptible, infected, treatment and recovered (SITR) fractal systems of COVID-19 propagation and control. The structure of an error function is accessible using the SITR differential form and its initial conditions. The optimization is performed using the MWNN together with the global as well as local search heuristics of genetic algorithm (GA) and active-set algorithm (ASA), i.e., MWNN-GA-ASA. The detail of each class of the SITR nonlinear COVID-19 system is also discussed. The obtained outcomes of the SITR system are compared with the Runge-Kutta results to check the perfection of the designed method. The statistical analysis is performed using different measures for 30 independent runs as well as 15 variables to authenticate the consistency of the proposed method. The plots of the absolute error, convergence analysis, histogram, performance measures, and boxplots are also provided to find the exactness, dependability and stability of the MWNN-GA-ASA.Article Citation - WoS: 12Citation - Scopus: 17Dynamics of Multi-Point Singular Fifth-Order Lane-Emden System With Neuro-Evolution Heuristics(Springer Heidelberg, 2022) Ali, Mohamed R.; Fathurrochman, Irwan; Raja, Muhammad Asif Zahoor; Sadat, R.; Baleanu, Dumitru; Sabir, ZulqurnainThe objective of the presented communication is to examine and analyze the solutions of nonlinear multi-singular fifth-order Lane-Emden (LE) system for different scenarios by variation of shape factors settled on the equivalent design of the LE equations. The neuro-evolution based stochastic computing is explored for the numerical measures using the artificial neural networks (ANNs) models for the appropriate continuous mapping, while the learning of decision variables is conducted using the integrated meta-heuristic global search of genetic algorithms (GA) hybrid with the local search efficiency of active-set (AS) i.e., ANN-GA-AS scheme. The numerical approach ANN-GA-AS is applied efficiently for the fifth kind of nonlinear LE model and statistical calculations further validate the accuracy, robustness as well as convergence.Article Citation - WoS: 8Citation - Scopus: 9A Hybrid Computing Approach To Design the Novel Second Order Singular Perturbed Delay Differential Lane-Emden Model(Iop Publishing Ltd, 2022) Baleanu, Dumitru; Raja, Muhammad Asif Zahoor; Hincal, Evren; Sabir, ZulqurnainIn this study, the mathematical form of the second order perturbed singular delay differential system is presented. The comprehensive features using the singular-point, perturbed factor and pantograph term are provided together with the shape factor of the second order perturbed singular delay differential system. The novel model is simulated numerically through the artificial neural networks (ANNs) based on the global/local optimization procedures, i.e., genetic algorithm (GA) and sequential quadratic programming (SQP). An activation function is constructed by using the differential model based on the second order perturbed singular delay differential system. The optimization of fitness function is performed through the hybrid computing strength of the ANNs-GA-SQP to solve the second order perturbed singular delay differential system. The exactness, substantiation, and authentication of the novel system is observed to solve three different variants of the novel model. The convergence, robustness, correctness, and stability of the numerical approach is performed using the comparison procedures of the available exact solutions. For the reliability, the statistical performances with necessary processes are provided using the ANNs-GA-SQP.Article Citation - WoS: 12Citation - Scopus: 15Numerical Solutions of a Novel Designed Prevention Class in the Hiv Nonlinear Model(Tech Science Press, 2021) Umar, Muhammad; Raja, Muhammad Asif Zahoor; Baleanu, Dumitru; Sabir, ZulqurnainThe presented research aims to design a new prevention class (P) in the HIV nonlinear system, i.e., the HIPV model. Then numerical treatment of the newly formulated HIPV model is portrayed handled by using the strength of stochastic procedure based numerical computing schemes exploiting the artificial neural networks (ANNs) modeling legacy together with the optimization competence of the hybrid of global and local search schemes via genetic algorithms (GAs) and active-set approach (ASA), i.e., GA-ASA. The optimization performances through GA-ASA are accessed by presenting an error-based fitness function designed for all the classes of the HIPV model and its corresponding initial conditions represented with nonlinear systems of ODEs. To check the exactness of the proposed stochastic scheme, the comparison of the obtained results and Adams numerical results is performed. For the convergence measures, the learning curves are presented based on the different contact rate values. Moreover, the statistical performances through different operators indicate the stability and reliability of the proposed stochastic scheme to solve the novel designed HIPV model.Article Citation - WoS: 60Citation - Scopus: 68Fractional Mayer Neuro-Swarm Heuristic Solver for Multi-Fractional Order Doubly Singular Model Based on Lane-Emden Equation(World Scientific Publ Co Pte Ltd, 2021) Raja, Muhammad Asif Zahoor; Baleanu, Dumitru; Sabir, ZulqurnainThis research is related to present a novel fractional Mayer neuro-swarming intelligent solver for the numerical treatment of multi-fractional order doubly singular Lane-Emden (LE) equation using combined investigations of the Mayer wavelet (MW) neural networks (NNs) optimized by the global search effectiveness of particle swarm optimization (PSO) and interior-point (IP) method, i.e. MW-NN-PSOIP. The design of novel fractional Mayer neuro-swarming intelligent solver for multi-fractional order doubly singular LE equation is derived from the standard LE model and the shape factors; fractional order terms along with singular points are examined. The modeling based on the MW-NN strength is implemented to signify the multi-fractional order doubly singular LE model using the ability of mean squared error in terms of the merit function and the networks are optimized with the integrated capability of PSOIP scheme. The perfection, verification and validation of the fractional Mayer neuro-swarming intelligent solver for three different cases of the multi-fractional order doubly singular LE equation are recognized through comparative investigations from the reference results on different measures based on the convergence, robustness, stability and accuracy. Furthermore, the statics interpretations further validate the performance of the proposed fractional Mayer neuro-swarming intelligent solvers.Article Citation - WoS: 37Citation - Scopus: 36Fmnsics: Fractional Meyer Neuro-Swarm Intelligent Computing Solver for Nonlinear Fractional Lane-Emden Systems(Springer London Ltd, 2022) Raja, Muhammad Asif Zahoor; Umar, Muhammad; Shoaib, Muhammad; Baleanu, Dumitru; Sabir, ZulqurnainThe fractional neuro-evolution-based intelligent computing has substantial potential to solve fractional order systems represented with Lane-Emden equation arising in astrophysics including Newtonian self-gravitating, spherically symmetric and polytropic fluid. The present study aimed to present a neuro-swarm-based intelligent computing solver for the solution of nonlinear fractional Lane-Emden system (NFLES) using by exploitation of fractional Meyer wavelet artificial neural networks (FMW-ANNs) and global optimization mechanism of particle swarm optimization (PSO) combined with rapid local search of sequential quadratic programming (SQP), i.e., FMW-ANN-PSO-SQP. The motivation for the design of FMW-ANN-PSO-SQP intelligent computing comes with an objective of presenting an accurate, reliable, and viable framworks to deal with stiff nonlinear singular models represented with NFLES involving both fractional and integer derivative terms. The designed algorithm is tested for six different variants of NFLESs. The obtained numerical outcomes obtained by the proposed FMW-ANN-PSO-SQP are compared with the exact results to authenticate the correctness, efficacy, and viability, and these aspects are further endorsed statistical observations.Article Citation - WoS: 62Citation - Scopus: 53Design of Stochastic Numerical Solver for the Solution of Singular Three-Point Second-Order Boundary Value Problems(Springer London Ltd, 2021) Baleanu, Dumitru; Shoaib, Muhammad; Raja, Muhammad Asif Zahoor; Sabir, ZulqurnainIn this paper, a novel meta-heuristic computing solver is presented for solving the singular three-point second-order boundary value problems using artificial neural networks (ANNs) optimized by the combined strength of global and local search ability of genetic algorithms (GAs) and interior point algorithm (IPA), i.e., ANN-GA-IPA. The inspiration for presenting this numerical work comes from the intention of introducing a consistent framework that combines the effective features of neural networks optimized with the contexts of soft computing to handle with such challenging systems. Three numerical variants of singular second-order system have been taken to examine the proficiency, robustness, and stability of the designed approach. The comparison of the proposed results of ANN-GA-IPA from available exact solutions shows the good agreement with 5 to 7 decimal places of the accuracy which established worth of the methodology through performance analyses on a single and multiple executions.
