Lensfree On-Chip Fluorescence Microscopy for High-Throughput Imaging of Bio-Chips

Abstract

On-chip fluorescence microscopy is an emerging platform that enables high-throughput screening of bio-chips over a wide field-of-view without the use of any lenses, thin-film filters or mechanical scanners. In this review, we summarize the recent advances in lensfree fluorescence microscopy and also discuss some of its unique capabilities toward high-throughput screening applications, including rare-cell imaging, on-chip cytometry and as well as micro-array research. © 2014 Springer Science+Business Media.