Browsing by Author "Ozcan, A."

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    High-Throughput Screening of Blood Samples Based on Structured Illumination On-Chip Imaging
    (IEEE, 2013) Arpali, Serap; Arpali, S.A.; Arpali, Çağlar; Arpali, C.; Coskun, A.F.; Chiang, H.-H.; Ozcan, A.; Mekatronik Mühendisliği; Elektronik ve Haberleşme Mühendisliği
    We demonstrate a high-throughput fluorescent on-chip imaging platform, using structured illumination that can rapidly screen large volumes of scattering media such as undiluted whole blood samples (e.g., ~ 0.3-0.7 mL) for detection of fluorescent micro-objects at low concentrations (e.g.,≤50-100 particles/mL). This imaging modality might especially be useful for rare cell applications involving whole blood samples, such as detection of circulating tumor cells. © 2013 OSA.
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    Lensfree On-Chip Fluorescence Microscopy for High-Throughput Imaging of Bio-Chips
    (2014) Coskun, A.F.; Arpali, S.A.; Arpali, C.; Su, T.-W.; Sencan, I.; Herman, D.; Ozcan, A.
    On-chip fluorescence microscopy is an emerging platform that enables high-throughput screening of bio-chips over a wide field-of-view without the use of any lenses, thin-film filters or mechanical scanners. In this review, we summarize the recent advances in lensfree fluorescence microscopy and also discuss some of its unique capabilities toward high-throughput screening applications, including rare-cell imaging, on-chip cytometry and as well as micro-array research. © 2014 Springer Science+Business Media.